Sevoflurane 250ml

Description

### SEVOFLURANE

**1. Drug Name and Description**:
– **Brand Name**: Ultane (commonly used brand)
– **Generic Name**: Sevoflurane
– **Description**: Sevoflurane is a volatile liquid anesthetic used for inhalation. It is clear, colorless, and nonflammable.

**2. Uses**:
– Sevoflurane is used to induce and maintain general anesthesia in patients undergoing surgery.

**3. Dosage and Administration**:
– **Recommended Dosage**: The concentration of sevoflurane delivered from a vaporizer should be titrated based on the desired depth of anesthesia. Typical concentrations range from 1% to 8%.
– **Administration**: Sevoflurane is administered via inhalation using a precision vaporizer calibrated specifically for sevoflurane.

**4. Mechanism of Action**:
– Sevoflurane works by depressing the central nervous system, which leads to a reversible loss of consciousness and sensation. It enhances the activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and inhibits the excitatory neurotransmitter N-methyl-D-aspartate (NMDA) receptors.

**5. Side Effects**:
– **Common Side Effects**: Nausea, vomiting, hypotension, and respiratory depression.
– **Severe Side Effects**: Malignant hyperthermia, hepatic dysfunction, and rare instances of allergic reactions.

**6. Warnings and Precautions**:
– **Safety Information**: Sevoflurane can cause malignant hyperthermia in susceptible individuals. Anesthesia with sevoflurane should be administered by professionals trained in the administration of general anesthesia.
– **Who Should Avoid**: Individuals with a known or suspected susceptibility to malignant hyperthermia or those with a history of hypersensitivity to sevoflurane or other halogenated anesthetics.

**7. Drug Interactions**:
– **Interactions**: Sevoflurane can interact with other central nervous system depressants, leading to enhanced sedative effects. It may also interact with non-depolarizing muscle relaxants, prolonging their action.
– **Management**: Inform the anesthesiologist of all medications and supplements the patient is taking to avoid potential interactions.

**8. Storage Instructions**:
– **Storage**: Store sevoflurane at room temperature, away from sources of ignition. Ensure the container is tightly closed and kept in a well-ventilated area.

**9. Spotting Fake Drugs**:
– **Signs of Counterfeit Drugs**: Authentic sevoflurane should come in professionally sealed bottles with proper labeling, including the concentration and manufacturer information. Check for any irregularities in packaging or labeling.
– **Tips**: Purchase sevoflurane only from licensed medical supply distributors. Verify the authenticity of the product with the supplier if in doubt.

**10. Authorized Sellers**:
– Sevoflurane should be obtained through authorized medical supply distributors or pharmacies. Ensure that the supplier is reputable and licensed.